5-hydroxy-1H,7H-imidazo[1,2-a]pyrimidin-7-one

5-hydroxy-1H,7H-imidazo[1,2-a]pyrimidin-7-one - Names and Identifiers

Name	5,7-Dihydroxyimidazo[1,2-a]pyrimidine
Synonyms	imidazo[1,2-a]pyrimidine-5,7-diol iMidazo[1,2-a]pyriMidine-5,7-diol 5,7-Dihydroxyimidazo[1,2-a]pyrimidine 5,7-Dihydroxyimidazo[1,2-α]pyrimidine 5-Hydroxyimidazo[1,2-a]pyrimidin-7(8H)-one 7-Hydroxyimidazo[1,2-a]pyrimidin-5(8H)-one 5-hydroxyimidazo[1,2-a]pyrimidin-7(1H)-one 5-hydroxyimidazo[1,2-α]pyrimidin-7(1H)-one Imidazo[1,2-a]pyrimidin-7(8H)-one, 5-hydroxy- IMidazo[1,2-a]pyriMidin-7(1H)-one, 5-hydroxy- 5-hydroxy-1H,7H-imidazo[1,2-a]pyrimidin-7-one
CAS	51647-90-6
InChI	InChI=1/C6H5N3O2/c10-4-3-5(11)9-2-1-7-6(9)8-4/h1-3,11H,(H,7,8,10)

5-hydroxy-1H,7H-imidazo[1,2-a]pyrimidin-7-one - Physico-chemical Properties

Molecular Formula	C6H5N3O2
Molar Mass	151.12
Density	1.74±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point	>260°C (dec.)
Solubility	DMSO, Methanol
Appearance	Solid
Color	Off-White
pKa	4.50±1.00(Predicted)
Storage Condition	2-8°C
Refractive Index	1.793

5-hydroxy-1H,7H-imidazo[1,2-a]pyrimidin-7-one - Introduction

5,7-Dihydroxyimidazo[1,2-a]pyrimidine is an organic compound with the chemical formula C5H4N4O2 and a molecular weight of 140.11g/mol. It has a white or white-like crystalline powder. The following is a description of the nature, use, manufacture and safety information of 5,7-Dihydroxyimidazo[1,2-a]pyrimidine:

Nature:
-Appearance: white or white-like crystalline powder
-melting point:>300 ℃ (decomposition)
-Soluble: Soluble in water and many organic solvents
-chemical properties: under the action of oxidizing agent, oxidation reaction may occur, need to be careful to use

Use:
- 5,7-Dihydroxyimidazo[1,2-a]pyrimidine is an important organic synthesis intermediate, which is widely used in the fields of drug synthesis, dye synthesis and organic photoelectric materials.
-It can be used as an intermediate in the oxalic acid pathway for the synthesis of certain anti-cancer drugs and antibiotics.

Preparation Method:
- 5,7-Dihydroxyimidazo[1,2-a]pyrimidine has many synthesis methods. The common methods include using 2,4, 6-trihydroxyimidazole as a raw material and synthesizing by a cyclosynthesis reaction under acidic conditions.
-During the synthesis process, it is necessary to pay attention to factors such as operating temperature and reaction time to ensure the effective progress of the synthesis reaction.

Safety Information:
- 5,7-Dihydroxyimidazo[1,2-a]pyrimidine has low toxicity and danger, but it is still necessary to pay attention to safe operation.
-When using or handling, avoid direct contact with skin and eyes, and wear protective gloves, goggles and other personal protective equipment when using.
-If inhaled accidentally or ingested by mistake, please seek medical attention promptly.

Last Update：2024-04-09 19:05:50